Pediatric Emergencies
A 21-day-old term infant is brought at 2 am by anxious first-time parents with a rectal temperature of 38.4 degrees, poor feeding for twelve hours and increasing sleepiness. He looks mottled with a capillary refill of three seconds, heart rate 190, respiratory rate 62, and is difficult to rouse for examination. The parents ask whether you can just give something for the fever and let them go home. How would you proceed?
What the panel is testing: The panel is testing the mandatory approach to the febrile neonate, recognition of paediatric sepsis, and the ability to communicate necessity and uncertainty to frightened parents who want to leave.
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Knowledge: A fever of 38 degrees or more in an infant under 28 days is an emergency until proven otherwise, because neonates have immature immunity, an unreliable clinical examination and a high rate of invasive bacterial infection, and this baby additionally has signs of poor perfusion and respiratory distress which mean he is not simply febrile, he is potentially septic.
Management: This is a resuscitation-room case. I would attach monitoring, check a capillary glucose immediately and correct hypoglycaemia with 2 mL/kg of 10 percent dextrose, give oxygen as required, and obtain intravenous access, moving to intraosseous access without prolonged delay if two attempts fail. The full septic screen means blood culture, full blood count, C-reactive protein and procalcitonin where available, blood gas with lactate, urine by catheter or suprapubic aspirate rather than a bag specimen, and a lumbar puncture.
Ethics and communication: The parents' request to go home is fear, not neglect, and the way I respond determines whether they cooperate for the next twelve hours. I would sit down, use their language or an interpreter, explain in concrete terms that at three weeks of age a fever with these signs carries a real risk of a blood or brain infection that we cannot exclude by examination, and that the tests and antibiotics are urgent rather than precautionary.
Likely panel follow-up questions
- Why do the low-risk febrile infant criteria not apply to this baby?
- You cannot get intravenous access after two attempts. What is your next step and what is your antibiotic timing target?
- What features would make you add aciclovir, and what is the evidence for empiric use?
Pitfalls in this case
- Applying low-risk febrile infant rules to an infant under 22 days or to an ill-appearing infant
- Sending a bag urine specimen and treating on its result
- Delaying antibiotics until after a difficult lumbar puncture
Reference: American Academy of Pediatrics Clinical Practice Guideline: Evaluation and Management of Well-Appearing Febrile Infants 8 to 60 Days Old (Pediatrics, 2021); NICE NG143 Fever in Under 5s (updated 2021)